Do Chefs Value Health in Their Olive Oil Purchasing Decisions?

Amidst the public's growing preoccupation with healthy eating, both inside and outside the home; an increase in people eating out; and the importance that olive oil has acquired in the markets due to its health benefits, the aim of this study is to find out whether health is also a relevant criterion for chefs in their olive oil purchase decisions. To this end, a survey was conducted of 400 chefs in Spain belonging to the international chefs' association Euro-Toques. The results show that only 2% of the sample consider health to be a relevant criterion in the purchase of olive oils and that the attribute of "health" is not used by restaurants as an element of differentiation by which to position themselves in the market. These results lead us to conclude that the consumer demand for healthy foods (in this case, olive oils) is not being met by the restaurant sector. Moreover, this raises the question as to whether chefs actually make good opinion leaders, with all that this social role implies.

Penn State Worry Questionnaire-11 validity in Colombia and factorial equivalence across gender and nonclinical and clinical samples / Validez del Penn State Worry Questionnaire-11 en Colombia y equivalencia factorial a través de género y muestras clínicas y no clínicas

The Penn State Worry Questionnaire (PSWQ) is the gold standard measure of the unspecific worry that characterizes generalized anxiety disorder. This study aims to explore the validity of the PSWQ in Colombia and its measurement invariance across gender and clinical and nonclinical participants. An abbreviated, 11-item version of the PSWQ by Sandín, Chorot, Valiente, and Lostao (2009) was used because the negatively worded items have shown to be problematic for Spanish speakers. Additionally, research has suggested that the negatively worded items of the PSWQ lack of practical utility. The PSWQ-11 was administered to a total of 1045 participants, including a sample of nonclinical participants (N = 710) and a sample of clinical participants (N = 335). The internal consistency of the PSWQ-11 across samples was excellent. The one-factor model showed an acceptable fit to the data. Metric and scalar invariance were observed across gender and clinical and nonclinical samples. In conclusion, the PSWQ-11 seems to be a valid measure of GAD-related worry in Colombia, whereas data on factorial equivalence data warrant the comparison of scores across gender and clinical and nonclinical samples

El Penn State Worry Questionnaire (PSWQ) es la medida principal de la preocupación inespecífica que caracteriza al trastorno de ansiedad generalizada (TAG). Este estudio explora la validez del PSWQ en Colombia y su invarianza de medida entre género y participantes clínicos y no clínicos. Se utilizó la versión abreviada de 11 ítems de PSWQ propuesta por Sandín, Chorot, Valiente y Lostao (2009) porque los ítems redactados negativamente han mostrado ser problemáticos para los hispanohablantes. Adicionalmente, la investigación ha sugerido que los ítems redactados en negativa carecen de utilidad práctica. El PSWQ-11 se administró a un total de 1045 participantes, incluyendo una muestra de participantes no clínicos (N = 710) y una muestra de participantes clínicos (N = 335). La consistencia interna del PSWQ-11 a través de muestras fue excelente. El modelo de un factor mostró un ajuste aceptable a los datos. Se observó invarianza métrica y escalar a través de género y muestras clínicas y no clínicas. En conclusión, el PSWQ-11 parece ser una medida válida de la preocupación tipo TAG, mientras que los datos sobre equivalencia factorial permiten la comparación de puntuaciones a través de género y participantes clínicos y no clínicos

Utility intervention programs in the evolutional control of patients with heart failure / Utilidad de los programas de intervención en el control evolutivo de los pacientes con insuficiencia cardiaca.

Acute heart failure (HF) is a prevalent disease with important socio-economic repercussions. Due to the aging of population, these values will increase in the coming years, so it may be useful to the implementation of intervention programs in these patients to decrease morbidity and mortality. A quasi-experimental prospective study (n = 262) of patients admitted at the Internal Medicine Department of the Hospital Clínico Universitario Lozano Blesa, in Zaragoza, Spain, diagnosed of HF between November 2013 and October 2014 (both dates inclusive) (n = 108) followed up for 1 year was performed. Within this group, a subgroup with an intensive intervention (n = 30) was performed. The data were compared with a historical cohort of patients admitted to the same department during the same time in the previous year (from November 2012 to October 2013) (n = 154). Statistically significant differences between groups attending to the therapeutical adherence to clinical guidelines (p < 0.011) were observed. Considering the intensive intervention subgroup, statistically significant differences were observed in the rate of exitus (p < 0.032) and survival (log rank <0.030) compared to the control group. The close monitoring of patients with HF improves adherence, reduces mortality and improves survival. This May result in a decline in the use of health resources, which entails significant socio-economic benefits.

Vapour-liquid interfacial properties of square-well chains from density functional theory and Monte Carlo simulation.

The statistical associating fluid theory for attractive potentials of variable range (SAFT-VR) density functional theory (DFT) developed by [Gloor et al., J. Chem. Phys., 2004, 121, 12740-12759] is used to predict the interfacial behaviour of molecules modelled as fully-flexible square-well chains formed from tangentially-bonded monomers of diameter σ and potential range λ = 1.5σ. Four different model systems, comprising 4, 8, 12, and 16 monomers per molecule, are considered. In addition to that, we also compute a number of interfacial properties of molecular chains from direct simulation of the vapour-liquid interface. The simulations are performed in the canonical ensemble, and the vapour-liquid interfacial tension is evaluated using the wandering interface (WIM) method, a technique based on the thermodynamic definition of surface tension. Apart from surface tension, we also obtain density profiles, coexistence densities, vapour pressures, and critical temperature and density, paying particular attention to the effect of the chain length on these properties. According to our results, the main effect of increasing the chain length (at fixed temperature) is to sharpen the vapour-liquid interface and to increase the width of the biphasic coexistence region. As a result, the interfacial thickness decreases and the surface tension increases as the molecular chains get longer. The interfacial thickness and surface tension appear to exhibit an asymptotic limiting behaviour for long chains. A similar behaviour is also observed for the coexistence densities and critical properties. Agreement between theory and simulation results indicates that SAFT-VR DFT is only able to predict qualitatively the interfacial properties of the model. Our results are also compared with simulation data taken from the literature, including the vapour-liquid coexistence densities, vapour pressures, and surface tension.

Acerca de las oportunidades de mejora en el manejo de la sepsis grave y el shock séptico en urgencias / Management of severe sepsis and septic shock in a tertiary care urban hospital emergency department: opportunities for improvement

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Melatonin's role in preventing toxin-related and sepsis-mediated hepatic damage: A review.

The liver is a central organ in detoxifying molecules and would otherwise cause molecular damage throughout the organism. Numerous toxic agents including aflatoxin, heavy metals, nicotine, carbon tetrachloride, thioacetamide, and toxins derived during septic processes, generate reactive oxygen species followed by molecular damage to lipids, proteins and DNA, which culminates in hepatic cell death. As a result, the identification of protective agents capable of ameliorating the damage at the cellular level is an urgent need. Melatonin is a powerful endogenous antioxidant produced by the pineal gland and a variety of other organs and many studies confirm its benefits against oxidative stress including lipid peroxidation, protein mutilation and molecular degeneration in various organs, including the liver. Recent studies confirm the benefits of melatonin in reducing the cellular damage generated as a result of the metabolism of toxic agents. These protective effects are apparent when melatonin is given as a sole therapy or in conjunction with other potentially protective agents. This review summarizes the published reports that document melatonin's ability to protect hepatocytes from molecular damage due to a wide variety of substances (aflatoxin, heavy metals, nicotine, carbon tetrachloride, chemotherapeutics, and endotoxins involved in the septic process), and explains the potential mechanisms by which melatonin provides these benefits. Melatonin is an endogenously-produced molecule which has a very high safety profile that should find utility as a protective molecule against a host of agents that are known to cause molecular mutilation at the level of the liver.

Psychometric properties of the Mindful Attention Awareness Scale in Colombian undergraduates / Propiedades psicométricas de la Mindful Attention Awareness Scale en universitarios colombianos

The Mindfulness Attention Awareness Scale is one of the most popular instruments to measure mindfulness, and this construct is conceived as unidimensional, emphasizing attention/awareness as its essential aspect. This study aimed to analyze the factor structure and psychometric properties of the Spanish version of the MAAS in a Colombian sample of 762 undergraduates. Data were very similar to those obtained in other validation studies of the MAAS. A confirmatory factor analysis found that the expected one-factor structure showed a good fit to the data. The MAAS had excellent internal consistency, and showed theoretically coherent correlations with emotional symptoms, automatic negative thoughts, psychological inflexibility, and life satisfaction. Participants who could have a psychopathological problem because they exceeded the cut-off of the General Health Questionnaire, 12 scored lower on the MAAS than participants who scored below this cut-off. In conclusion, the MAAS seems to be a reliable and valid measure of mindfulness in Colombian undergraduates.

La Mindfulness Attention Awareness Scale es uno de los instrumentos más populares para medir mindfulness, concibe este constructo como unidimensional y subraya el aspecto esencial de la atención/conciencia. Este estudio pretende analizar la estructura factorial y las propiedades psicométricas de la versión en español de la MAAS en una muestra de 762 universitarios colombianos. Los resultados fueron muy similares a los obtenidos en otros estudios de validación. El análisis factorial confirmatorio encontró que la estructura unifactorial esperada mostró un buen ajuste a los datos. La MAAS tuvo una consistencia interna excelente y mostró correlaciones teóricamente coherentes con síntomas emocionales, pensamientos automáticos negativos, inflexibilidad psicológica y satisfacción vital. Los participantes que podían tener algún problema psicopatológico por exceder el punto de corte del General Health Questionnaire - 12, puntuaron más bajo en la MAAS que los participantes que puntuaron por debajo de este punto de corte. En conclusión, la MAAS parece ser una medida fiable y válida de mindfulness en universitarios colombianos.

Comentarios acerca del estudio PROTESU / Comment on the PROTESU study

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Prognostic value of serum cystatin C and N-terminal pro b-type natriuretic peptide in patients with acute heart failure.

BACKGROUND: Cystatin C (CysC) is a good prognostic marker in heart failure. However, there is not much information of CysC combined with other biomarkers in acute heart failure (AHF). AIM: To assess prognostic value of CysC and N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients hospitalized for AHF with no apparent deterioration of renal function. DESIGN: Prospective, multicenter, observational study. METHODS: CysC and NTpro-BNP were measured in patients consecutively admitted with a diagnosis of AHF. Patients with, NTpro-BNP concentration above 900 pg/mL and serum creatinine below 1.3mg/dL, were included for statistical analysis. End-point of the study was all-cause mortality during a 12-month follow-up. RESULTS: 526 patients with AHF and NTpro-BNP concentration above 900 pg/mL were included in the study. From this group, 367 patients (69.8%) had serum creatinine below 1.3mg/dL. Receiver operating characteristic (ROC) curves were used to determine the best cut-off value for CysC. Patients with a concentration of CsyC above 1.25mg/dL had a 37.8% mortality rate, vs. 13.6% for those below cut-off (p<0.001). After Cox proportional hazard model, age, CysC, low total cholesterol and HF with preserved ejection fraction remained significantly associated with all-cause mortality during one-year follow-up. CONCLUSIONS: In AHF and normal or slightly impaired renal function, performance of CysC may be superior to NT-proBNP. Hence, CysC may be the preferred biomarker in the assessment of patients with AHF and slightly impaired renal function.

La cistatina C: una proteína para la insuficiencia cardíaca / Cystatin C: A protein for heart failure

La cistatina C es una proteína con actividad antiproteásica que se ha utilizado para la estimación de la función renal. Más allá de esta propiedad, aporta una información pronóstica en diferentes aspectos de la enfermedad cardiovascular. Se revisan los datos que avalan su utilidad como factor pronóstico cardiovascular en sujetos sanos de edad avanzada, hipertensos e insuficientes cardíacos. Se ha postulado que puede ser un marcador precoz de remodelado cardíaco, probablemente por hallarse involucrada en la patogenia de este, como un factor antiproteásico local en el miocardio. Su papel en la fisiopatología y clínica cardiovascular está por determinarse (AU)

Cystatin C (CysC) is an antiprotease useful for measuring kidney function. Beyond such property, it carries significant prognostic information in several fields of cardiovascular diseases. We review data that support CysC as a prognostic factor in cardiovascular diseases among healthy elderly, hypertensive and heart failure patients. In addition, it has been speculated that CysC may be an early marker of ventricular remodelling, primarily involved in its pathogenesis, as a local antiprotease. Its role in physiopathology and clinical issues of cardiovascular pathology is yet to be elucidated (AU)

[Cystatin C: a protein for heart failure]. / La cistatina C: una proteína para la insuficiencia cardíaca.

Cystatin C (CysC) is an antiprotease useful for measuring kidney function. Beyond such property, it carries significant prognostic information in several fields of cardiovascular diseases. We review data that support CysC as a prognostic factor in cardiovascular diseases among healthy elderly, hypertensive and heart failure patients. In addition, it has been speculated that CysC may be an early marker of ventricular remodelling, primarily involved in its pathogenesis, as a local antiprotease. Its role in physiopathology and clinical issues of cardiovascular pathology is yet to be elucidated.

Differential prognostic utility of NTproBNP and Cystatin C in patients with acute exacerbation of chronic pulmonary disease.

OBJECTIVES: To determine whether serum Cystatin C (CysC) and NTproBNP have prognostic value among patients with long-standing chronic lung disease. DESIGN: Prospective, observational, non-interventional study. SETTING: CysC and NTproBNP are prognostic markers in several cardiac conditions. In addition, CysC acts as an antiprotease following Cathepsin activation, which has been involved in the pathogenesis of chronic obstructive pulmonary disease. PARTICIPANTS: Patients with a basal functional status of II-IV (NYHA), admitted for an acute exacerbation of chronic pulmonary diseases and no previous history of symptoms related to pulmonary hypertension or heart failure. MAIN OUTCOME MEASURES: NTproBNP and CysC were determined at admission in 107 patients with acute exacerbation of chronic lung disease. During 12-month follow-up, mortality, new hospital admissions and prescription of diuretics were recorded. RESULTS: During follow-up there were eight patient deaths (7.5%). Mean NTproBNP among the deceased was 1510.20 pg/mL (95% CI 498.44-4628.55) vs 502.70 pg/mL (95% CI 395.44-645.48) among survivors (p = 0.01). Twenty-seven patients (25%) were prescribed loop diuretics. Mean concentration of CysC was 1.45 mg/dL (95% CI 1.21-1.69 mg/dL) vs 1.17 mg/dL (95% IC 1.09-1.25 mg/dL) in those not prescribed (p = 0.004). NTproBNP concentration was 837.14 pg/mL (95% CI 555.57-1274.10 pg/mL) in patients prescribed diuretics vs 473.42 pg/mL (95% CI 357.80-632.70 pg/mL) in those not prescribed (p = 0.03). Kaplan-Meier analysis revealed a significant difference between death and diuretic prescription during follow-up when cut-off value for NTproBNP was 550 pg/mL (p = 0.03 and p = 0.02, respectively). For 1.16mg/dL of CsysC, a significant difference was only observed in diuretic prescription (p = 0.007). CONCLUSIONS: In patients with chronic respiratory diseases NTproBNP has predictive value in terms of mortality whereas CysC does not. However, it is still possible that both can contribute to the early identification of patients at risk of developing clinical ventricular dysfunction.

Síndrome de Wallenberg y consumo de cannabis / Wallenberg syndrome and cannabis consumption

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Alternativas terapéuticas para la insuficiencia cardíaca en los ancianos: [revisión] / Therapeutic alternatives for treating heart failure in elderly patients: [review]

La insuficiencia cardíaca (IC) es una importante causa de mortalidad en todo el mundo y el principal motivo de hospitalización de origen no quirúrgico en muchos países. Existe un gran número de variables predictivas acerca del pronóstico de pacientes con IC, una de ellas es la edad. Además, la comorbilidad por causa no cardíaca dificulta el tratamiento en un importante grupo de pacientes ancianos con IC y casi la mitad de los pacientes con síntomas de IC presenta una fracción de eyección del ventrículo izquierdo conservada. Sin embargo, los ensayos clínicos en IC no se han centrado ni en el grupo de pacientes ancianos ni en aquellos con fracción de eyección conservada. Por esta razón no se han establecido recomendaciones específicas para este grupo. Este artículo revisará los estudios más importantes sobre IC realizados en los últimos años y analizará los resultados en pacientes de edad igual o superior a 65 años. Esta revisión incluye los betabloqueantes, inhibidores de la enzima convertidora de angiotensina, antagonistas del receptor de la angiotensina, antagonistas de los receptores de la aldosterona, nitratos más hidralazina, digoxina, estatinas, el desfibrilador automático implantable y la resincronización cardíaca.

Alternativas terapéuticas para la insuficiencia cardíaca en los ancianos: [revisión] / Therapeutic alternatives for treating heart failure in elderly patients: [review]

La insuficiencia cardíaca (IC) es una importante causa de mortalidad en todo el mundo y el principal motivo de hospitalización de origen no quirúrgico en muchos países. Existe un gran número de variables predictivas acerca del pronóstico de pacientes con IC, una de ellas es la edad. Además, la comorbilidad por causa no cardíaca dificulta el tratamiento en un importante grupo de pacientes ancianos con IC y casi la mitad de los pacientes con síntomas de IC presenta una fracción de eyección del ventrículo izquierdo conservada. Sin embargo, los ensayos clínicos en IC no se han centrado ni en el grupo de pacientes ancianos ni en aquellos con fracción de eyección conservada. Por esta razón no se han establecido recomendaciones específicas para este grupo. Este artículo revisará los estudios más importantes sobre IC realizados en los últimos años y analizará los resultados en pacientes de edad igual o superior a 65 años. Esta revisión incluye los betabloqueantes, inhibidores de la enzima convertidora de angiotensina, antagonistas del receptor de la angiotensina, antagonistas de los receptores de la aldosterona, nitratos más hidralazina, digoxina, estatinas, el desfibrilador automático implantable y la resincronización cardíaca.(AU)

Reincorporación laboral de trabajadores con cardiopatía, según el tipo de trabajo y la realización de un programa de rehabilitación cardiaca en Málaga / Return to work of workers with heart disease according to the type of work and attendance to a cardia rehabilitation program in Málaga

Justificación y objetivos: Las enfermedades más comunes asociadas al trabajo son los trastornos músculo-esqueléticos, las enfermedades dermatológicas y la alergia ocupacional. No obstante, las enfermedades cardiovasculares provocan la cuarta parte de accidentes de trabajo mortales que se producen en los centros de trabajo(1). Además son causas importantes de incapacidad laboral permanente, en pacientes con edad comprendida entre los 40 y 65 años, es decir, en pleno auge profesional. Los programas de rehabilitación cardiaca (PRC) han demostrado con creces su beneficio(2) en favor de una reincorporación laboral temprana y segura(3). El presente estudio pretende conocer la prevalencia de reincorporación laboral tras un evento cardia co, según el trabajo que desempeñan, en población laboral de Málaga; además del posible beneficio que aportan los PRC que siguen muchos de los pacientes que acuden por este motivo a unos de los dos grandes hospitales de la capital malagueña, y manifestar las posibles diferencias en reincorporación con pacientes similares y de la de la misma población pero que no tienen la oportunidad de participar en un PRC. Conclusiones: La reincorporación laboral, sobre todo en pacientes con riesgo medio-alto, fue mayor en el grupo que siguió un PRC, aunque la diferencia no resultó estadísticamente significativa. En cambio, sí hubo asociación entre reincorporación laboral y otras variables incluidas en el estudio, relacionadas con la enfermedad, factores socioeconómicos y características del trabaj (AU)

Justification and objetives: Most common diseases at work are skeletal muscle disorder, dermatological diseases and occupational allergy. However, cardiovascular diseases cause 25% of the mortal accidents in the companies during working hours(1). Besides, they are important causes of permanent labour disability, for patients who are 40-65 years old (i.e., during their highest professional time). Cardiac rehabilitation programs (CRP) have been proven as very benefitial(2) for a quick and safe labour reincorporation(3). This analysis tries to find out the prevalence of labour reincorporation after a cardiac event over the working population of Málaga (depending upon their roles at work) as well as the potential benefits given by the CRP followed by most of the patients assisted in one of the largest hospital in the city, and manifest the potential differences in reincorporation with similar patients from the same place who have no opportunity to participate in a CRP. Conclusions: Labour reincorporation, especially on medium to high risk patients, was higher in the group that followed a CRP although the difference was not significant enough. On the other hand, there was a link between labour reincorporation and other variables used in the analysis which were related to disease, socio-economic factors and job characteristics (AU)